Infections with mycobacteria such as Mycobacterium tuberculosis are still a threat to human health and world-wide ~ 1.5 Mio. people die annually from Tuberculosis (WHO). Developing novel strategies to treat mycobacterial infections is inevitable, and our research efforts focus on the identification of novel protein drug targets with a spotlight on the mycobacterial membrane and extracellular space.
Research methods that we apply are divers and include: cell culture techniques (bacterial/mammalian), cloning and gene expression, protein production and analysis, native and SDS-page, western-blot, proteomics, organic synthesis, NMR and LC-MS analysis, as well as fluorescence microscopy.
